Aspirin And Ibuprofen Linked To Infertility In Men

Simon Moss
January 10, 2018

It is known to increase the risk of heart attacks and stroke if taken regularly in high doses for a long time. Researchers said the condition was mild in the men.

A new joint Danish-French research project has discovered that taking the medicament for only 14 days can cause damage to men's testosterone production, reports DR Nyheder. "Taken together, these in vivo data suggest that ibuprofen induced a state of compensated hypogonadism during the trial..." the study states. The 17 other volunteers were given a placebo pill.

A new study is hinting that a common over-the-counter painkiller, ibuprofen, may be linked to a male reproductive disorder. Testosterone production, however, did not increase concurrently, resulting in a lower ratio of testosterone to luteinizing hormone - a sign of hypogonadism, according to the paper.

A study published Monday in Proceedings of the National Academy of Sciences found that regular ibuprofen use may lead to compensated hypogonadism, a condition that can lead to infertility, erectile dysfunction, depression and loss of bone and muscle mass, among other symptoms. According to a recent study, however, regular consumption of the drug could lead to several side-effects, including male sterility.

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Richard Quinton, MD, from Newcastle University in England and the Society for Endocrinology, says: "This is a landmark study that elegantly combines clinical and basic research, at both tissue and cellular levels, to show that ibuprofen, a common over-the-counter painkiller, can reversibly hinder testosterone production by testicular cells". Otherwise, occasional use at the recommended dosage to treat aches and pains is safe and recommended.

The findings are certainly significant, as the 1,200mg of ibuprofen given to the participants each day is far below the suggested daily maximum of 3,200mg per day. "We are concerned about it, particularly for healthy people who don't need to take these drugs". If you're pregnant, taking blood thinners, or suffering from a serious medical condition, check with your doctor first before using.

The detrimental effects of daily ibuprofen were almost immediate.

Ibuprofen may be linked to male infertility, a study has found, and although the effects were reversible the long-term effects are unknown.

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